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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8690
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pubmed:dateCreated |
1990-4-16
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pubmed:abstractText |
To examine whether a variant human oestrogen receptor gene, which differs from the wild-type gene in the B region, was associated with spontaneous abortion, obstetric histories of breast cancer patients with this variant were compared with those of breast cancer patients with the wild-type gene. In women with the B-variant, 50% of pregnancies ended in spontaneous abortion, compared with 10% for women homozygous for the wild-type gene. B-variant women also had a higher proportion of spontaneous abortions and a higher number of spontaneous abortions per woman than did those with the wild-type gene.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
335
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
622-4
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1969015-Abortion, Habitual,
pubmed-meshheading:1969015-Breast Neoplasms,
pubmed-meshheading:1969015-Evaluation Studies as Topic,
pubmed-meshheading:1969015-Female,
pubmed-meshheading:1969015-Genotype,
pubmed-meshheading:1969015-Humans,
pubmed-meshheading:1969015-Polymorphism, Genetic,
pubmed-meshheading:1969015-Pregnancy,
pubmed-meshheading:1969015-RNA, Messenger,
pubmed-meshheading:1969015-Receptors, Estrogen,
pubmed-meshheading:1969015-Retrospective Studies
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pubmed:year |
1990
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pubmed:articleTitle |
Oestrogen receptor B-region polymorphism and spontaneous abortion in women with breast cancer.
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pubmed:affiliation |
Department of Radiotherapy, Mount Sinai School of Medicine, New York, NY 10029.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|