Source:http://linkedlifedata.com/resource/pubmed/id/19686466
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-1-11
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pubmed:abstractText |
The availability of safe replacement clotting factor concentrates together with effective antiviral drugs to treat human immunodeficiency and hepatitis C viruses and the provision of care at designated haemophilia treatment centres have resulted in a new phenomenon in haemophilia management - the ageing patient. Today, increasing numbers of persons with haemophilia (PWH) are middle-aged and older, and they face the same age-related health issues as the general population. The impact of these risks on PWH is unclear, however, and there is a paucity of information about how to manage comorbidities in this patient population. This review focuses on five comorbidities that uniquely affect older PWH: cardiovascular disease, liver disease, cancer, renal disease and joint disease. Available research is summarized and potential management approaches are suggested.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1365-2516
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1197-209
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pubmed:meshHeading |
pubmed-meshheading:19686466-Aged,
pubmed-meshheading:19686466-Blood Coagulation Factors,
pubmed-meshheading:19686466-Cardiovascular Diseases,
pubmed-meshheading:19686466-Comorbidity,
pubmed-meshheading:19686466-Factor VIII,
pubmed-meshheading:19686466-Hemophilia A,
pubmed-meshheading:19686466-Humans,
pubmed-meshheading:19686466-Joint Diseases,
pubmed-meshheading:19686466-Kidney Failure, Chronic,
pubmed-meshheading:19686466-Liver Diseases,
pubmed-meshheading:19686466-Male,
pubmed-meshheading:19686466-Middle Aged,
pubmed-meshheading:19686466-Neoplasms,
pubmed-meshheading:19686466-Practice Guidelines as Topic,
pubmed-meshheading:19686466-Risk Assessment
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pubmed:year |
2009
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pubmed:articleTitle |
Emerging clinical concerns in the ageing haemophilia patient.
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pubmed:affiliation |
Penn Comprehensive Hemophilia Program, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. barbara.konkle@uphs.upenn.edu
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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