Source:http://linkedlifedata.com/resource/pubmed/id/19666650
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2009-10-15
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| pubmed:abstractText |
The ventricular assist device (VAD) is a life-saving option for patients in heart failure refractory for conventional therapy. The aim of study was to assess the influence of VAD on heart transplantation (HT) outcome in children <16 years. Between October 1988 and August 2008, 73 children underwent HT: Group 1 (n=9) who received VAD as bridge to HT (left ventricular - 4, biventricular - 5), and Group 2 (n=64), without previous VAD. Diagnoses included cardiomyopathy (n=50 (68.5%)) and congenital heart defects (n=23 (31.5%)). Retrospective analysis of perioperative and long-term follow-up data was performed. The mean follow-up was 7.22+/-4.7 years. The diagnosis of cardiomyopathy appeared more often in Group 1 (P=0.074), but the difference was not significant. The two groups did not differ with respect to age (P=0.123) and weight (P=0.183). Mortality in long follow-up was: 11.1% (n=1) in Group 1 and 14.1% (n=9) in Group 2 (P=0.782). Analysis of preoperative end-organs function did not reveal significant differences between groups. There was also no significant differences with respect to waiting time for transplant (P=0.948), postoperative ventilatory support time (P=0.677), duration of hospital stay (P=0.711) and incidence of acute rejection episodes (P=0.156). VAD used as a bridge for HT in children does not negatively influence the outcome.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
|
| pubmed:issn |
1569-9285
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
9
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
807-10
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| pubmed:dateRevised |
2010-11-18
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| pubmed:meshHeading |
pubmed-meshheading:19666650-Adolescent,
pubmed-meshheading:19666650-Child,
pubmed-meshheading:19666650-Child, Preschool,
pubmed-meshheading:19666650-Female,
pubmed-meshheading:19666650-Graft Rejection,
pubmed-meshheading:19666650-Heart Failure,
pubmed-meshheading:19666650-Heart Transplantation,
pubmed-meshheading:19666650-Heart-Assist Devices,
pubmed-meshheading:19666650-Humans,
pubmed-meshheading:19666650-Infant,
pubmed-meshheading:19666650-Infant, Newborn,
pubmed-meshheading:19666650-Kaplan-Meier Estimate,
pubmed-meshheading:19666650-Length of Stay,
pubmed-meshheading:19666650-Male,
pubmed-meshheading:19666650-Miniaturization,
pubmed-meshheading:19666650-Prosthesis Design,
pubmed-meshheading:19666650-Pulsatile Flow,
pubmed-meshheading:19666650-Reoperation,
pubmed-meshheading:19666650-Respiration, Artificial,
pubmed-meshheading:19666650-Retrospective Studies,
pubmed-meshheading:19666650-Time Factors,
pubmed-meshheading:19666650-Treatment Outcome,
pubmed-meshheading:19666650-Waiting Lists
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Ventricular assist device as a bridge to heart transplantation in children.
|
| pubmed:affiliation |
Department of Cardiac Surgery, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany. mijanusz@cyf-kr.edu.pl
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| pubmed:publicationType |
Journal Article
|