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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2009-10-22
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pubmed:abstractText |
Use of etomidate in the critically ill is controversial due to its links with an inadequate response to corticotropin and potential for excess mortality. In a septic shock population, we tested the hypotheses that etomidate administration induces more non-responders to corticotropin and increases mortality and that hydrocortisone treatment decreases mortality in patients receiving etomidate.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1432-1238
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pubmed:author |
pubmed-author:AnnaneDjillaliD,
pubmed-author:ChevretSylvieS,
pubmed-author:CuthbertsonBrian HBH,
pubmed-author:FreivogelKlausK,
pubmed-author:GarfieldMarkM,
pubmed-author:GoodmanSergeS,
pubmed-author:LaterrePierre-FrancoisPF,
pubmed-author:PayenDidierD,
pubmed-author:ReinhartKonradK,
pubmed-author:SingerMervynM,
pubmed-author:SprungCharles LCL,
pubmed-author:VincentJean LouisJL,
pubmed-author:WeissYoram GYG
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pubmed:issnType |
Electronic
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1868-76
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pubmed:dateRevised |
2011-5-9
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pubmed:meshHeading |
pubmed-meshheading:19652948-Adrenal Glands,
pubmed-meshheading:19652948-Adrenocorticotropic Hormone,
pubmed-meshheading:19652948-Aged,
pubmed-meshheading:19652948-Analysis of Variance,
pubmed-meshheading:19652948-Anti-Inflammatory Agents,
pubmed-meshheading:19652948-Cause of Death,
pubmed-meshheading:19652948-Double-Blind Method,
pubmed-meshheading:19652948-Drug Antagonism,
pubmed-meshheading:19652948-Etomidate,
pubmed-meshheading:19652948-Europe,
pubmed-meshheading:19652948-Female,
pubmed-meshheading:19652948-Humans,
pubmed-meshheading:19652948-Hydrocortisone,
pubmed-meshheading:19652948-Hypnotics and Sedatives,
pubmed-meshheading:19652948-Intensive Care,
pubmed-meshheading:19652948-Kaplan-Meier Estimate,
pubmed-meshheading:19652948-Logistic Models,
pubmed-meshheading:19652948-Male,
pubmed-meshheading:19652948-Middle Aged,
pubmed-meshheading:19652948-Multivariate Analysis,
pubmed-meshheading:19652948-Patient Selection,
pubmed-meshheading:19652948-Prospective Studies,
pubmed-meshheading:19652948-Severity of Illness Index,
pubmed-meshheading:19652948-Shock, Septic,
pubmed-meshheading:19652948-Statistics, Nonparametric,
pubmed-meshheading:19652948-Treatment Failure
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pubmed:year |
2009
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pubmed:articleTitle |
The effects of etomidate on adrenal responsiveness and mortality in patients with septic shock.
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pubmed:affiliation |
Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. b.h.cuthbertson@abdn.ac.uk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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