19640287

Source:http://linkedlifedata.com/resource/pubmed/id/19640287

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021756, umls-concept:C0025202, umls-concept:C0030705, umls-concept:C0036525, umls-concept:C0205390, umls-concept:C0205460, umls-concept:C1280500, umls-concept:C1522484, umls-concept:C1529682, umls-concept:C2603343
pubmed:dateCreated	2009-8-11
pubmed:abstractText	To explore the biological activity of EMD 273063 (hu14.18-IL2), a humanized anti-GD2 monoclonal antibody fused to interleukin-2 (IL2), in patients with unresectable, stage IV cutaneous melanoma as measured by induction of immune activation at the tumor site and in peripheral blood.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-10655437, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-10685652, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-12616104, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-14607902, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-15342808, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-15483010, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-16551859, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-16609058, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-16621991, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-18337646, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-18388930, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-18438664, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-2544891, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-8297135, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-8610104, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-8620525, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-8890894, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-9334808, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-9578424, http://linkedlifedata.com/resource/pubmed/commentcorrection/19640287-9780192
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101190741
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/EMD 273063 antibody, human, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2
pubmed:status	MEDLINE
pubmed:issn	1479-5876
pubmed:author	pubmed-author:AtkinsMichael BMB, pubmed-author:GilliesStephen DSD, pubmed-author:GoodingWilliamW, pubmed-author:KashalaOscarO, pubmed-author:KirkwoodJohn MJM, pubmed-author:KovarAndreasA, pubmed-author:MorseMichael AMA, pubmed-author:RibasAntoniA, pubmed-author:WhitesideTheresa LTL
pubmed:issnType	Electronic
pubmed:volume	7
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	68
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:19640287-Adult, pubmed-meshheading:19640287-Aged, pubmed-meshheading:19640287-Antibodies, Monoclonal, pubmed-meshheading:19640287-Area Under Curve, pubmed-meshheading:19640287-Biopsy, pubmed-meshheading:19640287-Cytokines, pubmed-meshheading:19640287-Female, pubmed-meshheading:19640287-Follow-Up Studies, pubmed-meshheading:19640287-Half-Life, pubmed-meshheading:19640287-Humans, pubmed-meshheading:19640287-Immunohistochemistry, pubmed-meshheading:19640287-Interleukin-2, pubmed-meshheading:19640287-Male, pubmed-meshheading:19640287-Melanoma, pubmed-meshheading:19640287-Metabolic Clearance Rate, pubmed-meshheading:19640287-Middle Aged, pubmed-meshheading:19640287-Neoplasm Metastasis, pubmed-meshheading:19640287-Neoplasm Staging, pubmed-meshheading:19640287-Skin Neoplasms, pubmed-meshheading:19640287-Time Factors, pubmed-meshheading:19640287-Treatment Outcome
pubmed:year	2009
pubmed:articleTitle	Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma.
pubmed:affiliation	University of California, 11-934 Factor Building, UCLA Medical Center, Los Angeles, CA 90095-1782, USA. aribas@mednet.ucla.edu
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Multicenter Study, Clinical Trial, Phase II, Clinical Trial, Phase I