Source:http://linkedlifedata.com/resource/pubmed/id/19631391
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-8-3
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pubmed:abstractText |
The objective of this study was to explore the response rate to high-frequency left-sided repetitive transcranial magnetic stimulation (rTMS) in patients who had failed to respond to right-sided low-frequency stimulation, and to investigate whether there was differential efficacy between stimulation at 5 or 10 Hz. Data from two randomized controlled trials were pooled. In both studies a group of patients were randomized to receive either 5- or 10-Hz left prefrontal rTMS after failing to respond to right-sided stimulation. These patients received blinded 5- or 10-Hz stimulation (but without a sham control) for a period of up to 4 weeks and outcomes were compared. There was a small but significant overall response to left-sided rTMS but no difference in response between the 5- and 10-Hz treatment conditions. There appears to be a significant but modest likelihood of response to left-sided TMS in patients who fail right-sided stimulation, but there is no difference in efficacy between 5- and 10-Hz stimulation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0165-1781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
169
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
12-5
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pubmed:dateRevised |
2009-12-16
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pubmed:meshHeading |
pubmed-meshheading:19631391-Adolescent,
pubmed-meshheading:19631391-Adult,
pubmed-meshheading:19631391-Aged,
pubmed-meshheading:19631391-Analysis of Variance,
pubmed-meshheading:19631391-Biophysics,
pubmed-meshheading:19631391-Depressive Disorder, Major,
pubmed-meshheading:19631391-Electric Stimulation,
pubmed-meshheading:19631391-Female,
pubmed-meshheading:19631391-Functional Laterality,
pubmed-meshheading:19631391-Humans,
pubmed-meshheading:19631391-Male,
pubmed-meshheading:19631391-Middle Aged,
pubmed-meshheading:19631391-Prefrontal Cortex,
pubmed-meshheading:19631391-Psychiatric Status Rating Scales,
pubmed-meshheading:19631391-Transcranial Magnetic Stimulation,
pubmed-meshheading:19631391-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
A study of the effectiveness of high-frequency left prefrontal cortex transcranial magnetic stimulation in major depression in patients who have not responded to right-sided stimulation.
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pubmed:affiliation |
Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Road, Melbourne, Victoria 3004, Australia. paul.fitzgerald@med.monash.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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