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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-11-25
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pubmed:abstractText |
It has been shown that neural stem cells (NSCs) migrate towards areas of brain injury or brain tumours and that NSCs have the capacity to track infiltrating tumour cells. The possible mechanism behind the migratory behaviour of NSCs is not yet completely understood. As chemokines are involved in the migration of immune cells in the injured brain, they may also be involved in chemoattraction of NSCs towards a brain tumour.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CXCR4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL12,
http://linkedlifedata.com/resource/pubmed/chemical/Cxcl12 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR4
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1365-2990
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-91
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pubmed:meshHeading |
pubmed-meshheading:19627512-Adult Stem Cells,
pubmed-meshheading:19627512-Animals,
pubmed-meshheading:19627512-Brain Neoplasms,
pubmed-meshheading:19627512-Calcium,
pubmed-meshheading:19627512-Cell Line, Tumor,
pubmed-meshheading:19627512-Cell Movement,
pubmed-meshheading:19627512-Chemokine CXCL12,
pubmed-meshheading:19627512-Chemotaxis,
pubmed-meshheading:19627512-Melanoma,
pubmed-meshheading:19627512-Mice,
pubmed-meshheading:19627512-Mice, Inbred C57BL,
pubmed-meshheading:19627512-Neoplasms, Experimental,
pubmed-meshheading:19627512-Neurons,
pubmed-meshheading:19627512-RNA, Messenger,
pubmed-meshheading:19627512-Receptors, CXCR,
pubmed-meshheading:19627512-Receptors, CXCR4,
pubmed-meshheading:19627512-Signal Transduction,
pubmed-meshheading:19627512-Stem Cell Niche
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pubmed:year |
2009
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pubmed:articleTitle |
The role of CXC chemokine ligand (CXCL)12-CXC chemokine receptor (CXCR)4 signalling in the migration of neural stem cells towards a brain tumour.
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pubmed:affiliation |
Departments of Neuroscience, University Medical Center Groningen, the Netherlands. a.a.e.van.der.meulen@med.umcg.nl
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pubmed:publicationType |
Journal Article
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