Source:http://linkedlifedata.com/resource/pubmed/id/19618378
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-2-16
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pubmed:abstractText |
The immune system (IS) plays a key role in the mechanisms underlying major depression (MD) and pro-inflammatory cytokines seem to be particularly involved in the pathogenesis of the disease. There is growing evidence of a relationship between commonly studied single nucleotide polymorphisms (SNPs) in cytokine genes and an increased risk of MD.The aim of our study was to investigate the association between the -308(G/A) SNP in the tumour necrosis factor-alpha (TNF-alpha) gene and late-life MD in elderly people without dementia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1099-1166
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2009 John Wiley & Sons, Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-23
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pubmed:dateRevised |
2011-2-8
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pubmed:meshHeading |
pubmed-meshheading:19618378-Aged,
pubmed-meshheading:19618378-Aged, 80 and over,
pubmed-meshheading:19618378-Depressive Disorder, Major,
pubmed-meshheading:19618378-Female,
pubmed-meshheading:19618378-Gene Frequency,
pubmed-meshheading:19618378-Genotype,
pubmed-meshheading:19618378-Humans,
pubmed-meshheading:19618378-Italy,
pubmed-meshheading:19618378-Male,
pubmed-meshheading:19618378-Polymorphism, Single Nucleotide,
pubmed-meshheading:19618378-Psychiatric Status Rating Scales,
pubmed-meshheading:19618378-Tumor Necrosis Factor-alpha
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pubmed:year |
2010
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pubmed:articleTitle |
The -308 (G/A) single nucleotide polymorphism in the TNF-alpha gene and the risk of major depression in the elderly.
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pubmed:affiliation |
Department of Clinical Medicine and Prevention, A.O. San Gerardo, University of Milan-Bicocca, Monza, Milan, Italy.
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pubmed:publicationType |
Journal Article
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