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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1976-3-11
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pubmed:abstractText |
In a double-blind trial lasting 2 weeks, a new, long-acting antihistamine, Mequitazine, and a placebo, were compared. 115 allergic patients participated in this experiment (mequitazine n = 56, placebo n = 59). Therapeutic results and the effect on diurnal alertness were evaluated by means of a questionnaire filled in daily by the patients. Whether considering the day by day results or the results of the entire treatment period, statistically, Mequitazine (10 mg/24 hrs) is very significantly more active than the placebo. The daytime drowsiness induced by Mequitazine is statistically no greater than that induced by the placebo, whether analyzed on a day by day basis or over the entire treatment period (P = 0.23). The side effects, 8 for Mequitazine, 5 for placebo, are mild and did not lead to discontinuation of the treatment in the Mequitazine group.
|
pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
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pubmed:issn |
0001-5148
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
286-97
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1959-Adult,
pubmed-meshheading:1959-Aged,
pubmed-meshheading:1959-Clinical Trials as Topic,
pubmed-meshheading:1959-Female,
pubmed-meshheading:1959-Histamine H1 Antagonists,
pubmed-meshheading:1959-Humans,
pubmed-meshheading:1959-Hypersensitivity,
pubmed-meshheading:1959-Male,
pubmed-meshheading:1959-Middle Aged,
pubmed-meshheading:1959-Phenothiazines,
pubmed-meshheading:1959-Placebos,
pubmed-meshheading:1959-Questionnaires,
pubmed-meshheading:1959-Quinuclidines,
pubmed-meshheading:1959-Time Factors
|
pubmed:year |
1975
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pubmed:articleTitle |
[Comparative study of a new antihistamine, mequitazine, and placebos].
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Randomized Controlled Trial,
Controlled Clinical Trial
|