Source:http://linkedlifedata.com/resource/pubmed/id/19530983
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2009-6-17
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pubmed:abstractText |
Tuberculosis (TB) remains the most important infectious disease causing morbidity and death, due to the human pathogen Mycobacterium tuberculosis. The emergence of multi-drug-resistant and extensively-drug-resistant forms of TB have resulted in an increase in the number of TB cases. Thus, there is an urgent need to identify new drugs with novel targets to ensure future therapeutic success. Studies have indicated that peptide deformylase is an interesting potential candidate for discovering antimicrobial agents.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1744-7631
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
753-65
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pubmed:meshHeading |
pubmed-meshheading:19530983-Amidohydrolases,
pubmed-meshheading:19530983-Animals,
pubmed-meshheading:19530983-Antitubercular Agents,
pubmed-meshheading:19530983-Drug Delivery Systems,
pubmed-meshheading:19530983-Drug Design,
pubmed-meshheading:19530983-Enzyme Inhibitors,
pubmed-meshheading:19530983-Humans,
pubmed-meshheading:19530983-Mycobacterium tuberculosis,
pubmed-meshheading:19530983-Tuberculosis,
pubmed-meshheading:19530983-Tuberculosis, Multidrug-Resistant
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pubmed:year |
2009
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pubmed:articleTitle |
Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery.
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pubmed:affiliation |
University of Notre Dame, Department of Biological Sciences, Notre Dame, IN-46556, USA.
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pubmed:publicationType |
Journal Article,
Review
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