Linked Life Data

19473858

Source:http://linkedlifedata.com/resource/pubmed/id/19473858

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-2-1
pubmed:abstractText
Infiltration anaesthesia with articaine, a local anaesthetic able to penetrate bone, may relieve procedural pain better than lidocaine in bone marrow aspiration and biopsy. This randomised, double-blind study comprised 150 patients with suspected or known haematologic disease. Either articaine 20mg/ml (50 patients), articaine 40mg/ml (49 patients) or lidocaine 20mg/ml (51 patients), all with adrenaline 5mug/ml, was infiltrated in volume of 6ml (sternal manubrium), 8ml (sternal body) or 10ml (iliac crest) 2min before puncture. Numeral rating scale score (median, range) at injection of local anaesthetic was 3.0 (0-10), at bone puncture 2.0 (0-8), at aspiration 3.5 (0-10) and at biopsy (48 patients) 3.0 (0-10). Pre-procedural anxiety, rated on a verbal scale, correlated significantly with experienced pain (P<0.01). Very anxious patients had fewer previous bone marrow examinations (P<0.01) and they experienced more pain during aspiration (P<0.05). In the post-interview 42 patients reported appearance of pain (median 2.0, range 1-7) after 6.2h, on average, and 15 patients needed oral analgesics. No parameter differed significantly between the groups. In conclusion, the quality of infiltration anaesthesia for bone marrow punctures and aspiration with articaine and lidocaine was similarly poor. Several patients experienced strong pain which correlated with the degree of anxiety.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1532-2149
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
160-3
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Comparison of articaine and lidocaine for infiltration anaesthesia in patients undergoing bone marrow aspiration and biopsy.
pubmed:affiliation
Department of Anaesthesiology and Intensive Care Medicine, University of Helsinki, Post-box 20, FIN-00014 Helsinki, Finland.
pubmed:publicationType
Journal Article, Comparative Study, Randomized Controlled Trial