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pubmed-article:19405744pubmed:abstractTextAccurate blood flow measurements during surgery can improve an operation's chance of success. We developed near-infrared spatio-temporal image spectroscopy (NIR-STICS), which has the potential to make blood flow measurements that are difficult to accomplish with existing methods. Specifically, we propose the technique and we show feasibility on phantom measurements. NIR-STICS has the potential of measuring the fluid velocity in small blood vessels (less than 1 mm in diameter) and of creating a map of blood flow rates over an area of approximately 1 cm(2). NIR-STICS employs near-infrared spectroscopy to probe inside blood vessel walls and spatiotemporal image correlation spectroscopy to directly-without the use of a model-extract fluid velocity from the fluctuations within an image. We present computer simulations and experiments on a phantom system that demonstrate the effectiveness of NIR-STICS.lld:pubmed
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pubmed-article:19405744pubmed:dateRevised2011-1-20lld:pubmed
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pubmed-article:19405744pubmed:articleTitleSpatiotemporal image correlation spectroscopy measurements of flow demonstrated in microfluidic channels.lld:pubmed
pubmed-article:19405744pubmed:affiliationUniversity of California Irvine, Biomedical Engineering Department, 3120 Natural Sciences 2, Irvine, California 92697-2715, USA. rossowm@uci.edulld:pubmed
pubmed-article:19405744pubmed:publicationTypeJournal Articlelld:pubmed
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