Linked Life Data

19321256

Source:http://linkedlifedata.com/resource/pubmed/id/19321256

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-6-22
pubmed:abstractText
Loss of cellular polarity/cohesiveness and periostin expression are involved in the epithelial-mesenchymal transition in the epithelial malignancies. Their roles in papillary thyroid carcinoma were studied. There was a significant correlation between the loss of cellular polarity/cohesiveness in the invasive front and the up-regulation of periostin in tumors. Both of them were significantly correlated with extrathyroid invasion, pT and lymph node metastasis. Our results suggest that the loss of cellular polarity/cohesiveness is a useful parameter for predicting prognosis of patients with papillary thyroid carcinoma, and periostin could be a candidate gene for therapeutic targeting for the blockage of tumor invasion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1872-7980
pubmed:author
pubmed:issnType
Electronic
pubmed:day
28
pubmed:volume
281
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
188-95
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Loss of cellular polarity/cohesiveness in the invasive front of papillary thyroid carcinoma and periostin expression.
pubmed:affiliation
Department of Pathology and Pathophysiology, Shandong University School of Medicine, Jinan, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't