Linked Life Data

19271941

Source:http://linkedlifedata.com/resource/pubmed/id/19271941

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-3-10
pubmed:abstractText
Trigeminal neuralgia leads to paroxysms of short-lasting but very severe pain. Between attacks, patients are usually asymptomatic, but a constant dull background pain may persist in some cases. The incidence of trigeminal neuralgia is 4.3 per 100,000 persons per year, with a slightly higher incidence for women (5.9 per 100,000) compared with men (3.4 per 100,000). There is a lack of certainty regarding the etiology and pathophysiology of trigeminal neuralgia. There are a wide range of medical and surgical treatments available. The preferred medical treatment for trigeminal neuralgia consists of anticonvulsant drugs, muscle relaxants and neuroleptic agents. Large-scaled placebo-controlled clinical trials are scarce. For patients refractory to medical therapy, Gasserian ganglion percutaneous techniques, gamma-knife surgery and microvascular decompression are the most promising invasive treatment options. Continuous scientific research works towards a better understanding of trigeminal neuralgia and has accomplished a greater insight into the underlying pathophysiological mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1744-8360
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-9
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Update on trigeminal neuralgia.
pubmed:affiliation
Department of Neurology, University of Duisburg-Essen, Essen, Germany. mark.obermann@uni-due.de
pubmed:publicationType
Journal Article, Review