Linked Life Data

19264730

Source:http://linkedlifedata.com/resource/pubmed/id/19264730

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-3-10
pubmed:abstractText
The pathogenesis of acute and recurrent anterior uveitis is poorly understood. Here, recent evidence is presented for the hypothesis that this disease may be associated with activation of receptors of the innate immune system, such as Toll-like receptors, by pathogen associated molecule patterns, such as lipopolysaccharide, derived from triggering gram negative bacteria. Acute anterior uveitis results in ocular tissue damage and the release of endogenous molecules (damage associated molecular patterns), such as heat shock proteins and S100 proteins that can also activate Toll-like receptors and thus perpetuate or reactivate intraocular inflammation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1468-2079
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
271-4
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The role of PAMPs and DAMPs in the pathogenesis of acute and recurrent anterior uveitis.
pubmed:affiliation
Laboratory of Ocular Immunology, Centre for Inflammation and Immunology, Faculty of Medicine University of New South Wales, Sydney, Australia. d.wakefield@unsw.edu.au
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't