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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-2-2
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pubmed:abstractText |
Lipoprotein lipase (LPL) has a prominent role in the metabolism of triglycerides (TGs) and high-density lipoprotein cholesterol (HDL-C) and is a potential interesting target for the development of antiatherogenic treatment. To provide deeper insight into the role of natural variation in this gene, we investigated the association between the LPL S447X variant with lipids and risk of coronary heart disease (CHD) in 3 independent, prospective studies.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1097-6744
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
157
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
384-90
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pubmed:dateRevised |
2011-10-31
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pubmed:meshHeading |
pubmed-meshheading:19185650-Adiposity,
pubmed-meshheading:19185650-Adult,
pubmed-meshheading:19185650-Aged,
pubmed-meshheading:19185650-Alcohol Drinking,
pubmed-meshheading:19185650-Case-Control Studies,
pubmed-meshheading:19185650-Coronary Disease,
pubmed-meshheading:19185650-Female,
pubmed-meshheading:19185650-Genotype,
pubmed-meshheading:19185650-Health Behavior,
pubmed-meshheading:19185650-Humans,
pubmed-meshheading:19185650-Lipids,
pubmed-meshheading:19185650-Lipoprotein Lipase,
pubmed-meshheading:19185650-Male,
pubmed-meshheading:19185650-Middle Aged,
pubmed-meshheading:19185650-Obesity,
pubmed-meshheading:19185650-Polymorphism, Single Nucleotide,
pubmed-meshheading:19185650-Prospective Studies,
pubmed-meshheading:19185650-Risk Factors,
pubmed-meshheading:19185650-Smoking
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pubmed:year |
2009
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pubmed:articleTitle |
S447X variant of the lipoprotein lipase gene, lipids, and risk of coronary heart disease in 3 prospective cohort studies.
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pubmed:affiliation |
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA. mkjensen@hsph.harvard.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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