Linked Life Data

19180523

Source:http://linkedlifedata.com/resource/pubmed/id/19180523

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-11-25
pubmed:abstractText
Bone ingrowth enhancement by the surface induced charges of the electrically polarized hydroxyapatite (HA)/beta-tricalcium phosphate (beta-TCP) ceramics was histologically investigated to clarify the early stage events of ossification. The HA/beta-TCP specimens with a relatively low porosity of 45% for bone ingrowth were polarized in a dc electric field at 400 degrees C for 1 h. The large preserved charges of 8 muC cm(-2) significantly promoted the bone ingrowth process of the porous ceramics implanted in femoral diaphyses of New Zealand white rabbits. The bone formation in the pores of the polarized HA/beta-TCP specimens was observed within 1 week after surgery. The bone occupancy of the polarized HA/beta-TCP pores reached more than 90% at as early as 2 weeks and significantly higher than that of the nonpolarized. The electrical polarization was proved to be effective for bone penetration improvement of low porosity ceramics. The electrically polarized HA/beta-TCP bone grafts with a lower porosity and a higher mechanical strength combined high osteoconductivity generated by the induced surface charges.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1552-4965
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
267-75
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Electrostatic surface charge acceleration of bone ingrowth of porous hydroxyapatite/beta-tricalcium phosphate ceramics.
pubmed:affiliation
Division of Inorganic Materials, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo 101-0062, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't