| pubmed-article:19178561 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19178561 | lifeskim:mentions | umls-concept:C0920317 | lld:lifeskim |
| pubmed-article:19178561 | lifeskim:mentions | umls-concept:C0376622 | lld:lifeskim |
| pubmed-article:19178561 | lifeskim:mentions | umls-concept:C1704939 | lld:lifeskim |
| pubmed-article:19178561 | lifeskim:mentions | umls-concept:C0003286 | lld:lifeskim |
| pubmed-article:19178561 | lifeskim:mentions | umls-concept:C1823242 | lld:lifeskim |
| pubmed-article:19178561 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:19178561 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:19178561 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:19178561 | pubmed:dateCreated | 2009-4-23 | lld:pubmed |
| pubmed-article:19178561 | pubmed:abstractText | Approximately one-third of patients with epilepsy patients have recurrent seizures despite therapy. It has been suggested that therapeutic failure is associated with high expression of the multidrug efflux ABCB1 (MDR1) drug-transporter; specifically, that patients with the 3435CC genotype have higher efflux of anticonvulsants out of brain tissue, with correspondingly lower concentrations in the central nervous system. | lld:pubmed |
| pubmed-article:19178561 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19178561 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19178561 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:19178561 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19178561 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19178561 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:19178561 | pubmed:issn | 1528-1167 | lld:pubmed |
| pubmed-article:19178561 | pubmed:author | pubmed-author:KorenGideonG | lld:pubmed |
| pubmed-article:19178561 | pubmed:author | pubmed-author:FinkelsteinYa... | lld:pubmed |
| pubmed-article:19178561 | pubmed:author | pubmed-author:JuurlinkDavid... | lld:pubmed |
| pubmed-article:19178561 | pubmed:author | pubmed-author:MorettiMyla... | lld:pubmed |
| pubmed-article:19178561 | pubmed:author | pubmed-author:BournissenFac... | lld:pubmed |
| pubmed-article:19178561 | pubmed:author | pubmed-author:WalkerMugabeM | lld:pubmed |
| pubmed-article:19178561 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19178561 | pubmed:volume | 50 | lld:pubmed |
| pubmed-article:19178561 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19178561 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19178561 | pubmed:pagination | 898-903 | lld:pubmed |
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| pubmed-article:19178561 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19178561 | pubmed:articleTitle | Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: a meta-analysis. | lld:pubmed |
| pubmed-article:19178561 | pubmed:affiliation | Divisions of Clinical Pharmacology and Toxicology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. | lld:pubmed |
| pubmed-article:19178561 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19178561 | pubmed:publicationType | Meta-Analysis | lld:pubmed |
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