rdf:type |
|
lifeskim:mentions |
umls-concept:C0007226,
umls-concept:C0025859,
umls-concept:C0032529,
umls-concept:C0032659,
umls-concept:C0034783,
umls-concept:C0422792,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1710133,
umls-concept:C2911692
|
pubmed:issue |
5
|
pubmed:dateCreated |
2008-11-26
|
pubmed:abstractText |
Beta-blockers show interindividual and interethnic variability in their response. Such variability might be due to the polymorphic variations in the beta1 adrenergic receptor genes viz, Ser49Gly and Arg389Gly. The study evaluated the influence of Ser49Gly and Arg389Gly polymorphisms on the cardiovascular responses to metoprolol in a South Indian population.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1533-4023
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
52
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
459-66
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:19033826-Adolescent,
pubmed-meshheading:19033826-Adrenergic beta-1 Receptor Antagonists,
pubmed-meshheading:19033826-Adrenergic beta-Antagonists,
pubmed-meshheading:19033826-Adult,
pubmed-meshheading:19033826-Exercise Test,
pubmed-meshheading:19033826-Gene Frequency,
pubmed-meshheading:19033826-Hemodynamics,
pubmed-meshheading:19033826-Humans,
pubmed-meshheading:19033826-India,
pubmed-meshheading:19033826-Male,
pubmed-meshheading:19033826-Metoprolol,
pubmed-meshheading:19033826-Middle Aged,
pubmed-meshheading:19033826-Polymorphism, Single Nucleotide,
pubmed-meshheading:19033826-Receptors, Adrenergic, beta-1,
pubmed-meshheading:19033826-Young Adult
|
pubmed:year |
2008
|
pubmed:articleTitle |
Genetic polymorphisms of beta1 adrenergic receptor and their influence on the cardiovascular responses to metoprolol in a South Indian population.
|
pubmed:affiliation |
Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry-605006, India.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|