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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-11-25
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pubmed:abstractText |
Cis-platinum and radiation in combination are current organ preservation treatment strategies for head and neck cancer. Their individual ototoxicity has been investigated, with recent demonstration of ototoxicity in clinical studies. Currently, no ototoxicity studies have been performed in animals receiving similar schedules of radiation or cis-platinum to those patients with head and neck cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1532-818X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-7
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pubmed:meshHeading |
pubmed-meshheading:19027506-Animals,
pubmed-meshheading:19027506-Auditory Threshold,
pubmed-meshheading:19027506-Cisplatin,
pubmed-meshheading:19027506-Combined Modality Therapy,
pubmed-meshheading:19027506-Disease Models, Animal,
pubmed-meshheading:19027506-Dose Fractionation,
pubmed-meshheading:19027506-Dose-Response Relationship, Drug,
pubmed-meshheading:19027506-Dose-Response Relationship, Radiation,
pubmed-meshheading:19027506-Evoked Potentials, Auditory, Brain Stem,
pubmed-meshheading:19027506-Guinea Pigs,
pubmed-meshheading:19027506-Hearing Loss, Sensorineural,
pubmed-meshheading:19027506-Probability,
pubmed-meshheading:19027506-Radiation Dosage,
pubmed-meshheading:19027506-Random Allocation,
pubmed-meshheading:19027506-Risk Assessment,
pubmed-meshheading:19027506-Sensitivity and Specificity
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pubmed:articleTitle |
Ototoxicity after combined platinum and fractionated radiation in a novel guinea pig model.
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pubmed:affiliation |
Otolaryngology Department, University of Minnesota, Minneapolis, MN, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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