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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-11-25
pubmed:abstractText
This cross-sectional study examined the burden of cardiovascular diseases (CVDs) using serum 25-hydroxyvitamin D (25[OH]D) and prevalence of hypovitaminosis D in adults with CVDs using data from NHANES 2001 to 2004. Serum 25(OH)D levels were divided into 3 categories (> or =30, 20 to 29, and <20 ng/ml), and hypovitaminosis D was defined as vitamin D <30 ng/ml. Of 8,351 adults who had 25(OH)D measured, mean 25(OH)D was 24.3 ng/ml, and the prevalence of hypovitaminosis D was 74%. The burden of CVDs increased with lower 25(OH)D categories, with 5.3%, 6.7%, and 7.3% coronary heart disease; 1.5%, 2.4%, and 3.2% heart failure; 2.5%, 2.0%, and 3.2% stroke; and 3.6%, 5.0%, and 7.7% peripheral arterial disease. Across all CVDs, hypovitaminosis D was more common in blacks than Hispanics or whites. Compared with persons at low risk for CVDs (68%), it was more prevalent in those at high risk (75%; odds ratio [OR] 1.32, 95% confidence interval [CI] 1.05 to 1.67), with coronary heart disease (77%; OR 1.48, 95% CI 1.14 to 1.91), and both coronary heart disease and heart failure (89%; OR 3.52, 95% CI 1.58 to 7.84) after controlling for age, race, and gender. In conclusion, hypovitaminosis D was highly prevalent in US adults with CVDs, particularly those with both coronary heart disease and heart failure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1879-1913
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
102
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1540-4
pubmed:meshHeading
pubmed-meshheading:19026311-Adult, pubmed-meshheading:19026311-African Americans, pubmed-meshheading:19026311-Aged, pubmed-meshheading:19026311-C-Reactive Protein, pubmed-meshheading:19026311-Cardiovascular Diseases, pubmed-meshheading:19026311-Confidence Intervals, pubmed-meshheading:19026311-Coronary Artery Disease, pubmed-meshheading:19026311-Cross-Sectional Studies, pubmed-meshheading:19026311-Dietary Supplements, pubmed-meshheading:19026311-European Continental Ancestry Group, pubmed-meshheading:19026311-Female, pubmed-meshheading:19026311-Heart Failure, pubmed-meshheading:19026311-Hispanic Americans, pubmed-meshheading:19026311-Humans, pubmed-meshheading:19026311-Male, pubmed-meshheading:19026311-Middle Aged, pubmed-meshheading:19026311-Odds Ratio, pubmed-meshheading:19026311-Prevalence, pubmed-meshheading:19026311-Risk Factors, pubmed-meshheading:19026311-United States, pubmed-meshheading:19026311-Vitamin D, pubmed-meshheading:19026311-Vitamin D Deficiency, pubmed-meshheading:19026311-Young Adult
pubmed:year
2008
pubmed:articleTitle
Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004).
pubmed:affiliation
Department of Medicine, Jefferson Medical College, Philadelphia, PA, USA.
pubmed:publicationType
Journal Article