| pubmed-article:18979182 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0150369 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0004153 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0449258 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0684321 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0032743 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C0031082 | lld:lifeskim |
| pubmed-article:18979182 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:18979182 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:18979182 | pubmed:dateCreated | 2009-2-16 | lld:pubmed |
| pubmed-article:18979182 | pubmed:abstractText | We investigated the ability of fluorodeoxyglucose positron emission tomography (FDG PET) imaging to serially monitor macrophage content in a rabbit model of atherosclerosis. Atherosclerosis was induced in rabbits (n = 8) by a combination of atherogenic diet and balloon denudation of the aorta. At the end of nine months, the rabbits were randomized to a further six months of the same atherogenic diet (progression group) or normal diet (regression group). In vivo uptake of FDG by the thoracic aorta was measured using aortic uptake-to-blood radioactivity ratios at the start and end of the randomized period. A significant increase in FDG uptake of the progression group after continued cholesterol feeding (aortic uptake-to-blood radioactivity: 0.57 +/- 0.02 to 0.68 +/- 0.02, P = 0.001), and a corresponding fall in FDG uptake of the regression group after returning to a normal chow diet (aortic uptake-to-blood radioactivity ratios: 0.67 +/- 0.02 to 0.53 +/- 0.02, P < 0.0001). FDG PET can quantify in vivo macrophage content and serially monitor changes in FDG activity in this rabbit model. | lld:pubmed |
| pubmed-article:18979182 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18979182 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18979182 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18979182 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18979182 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18979182 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18979182 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18979182 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:18979182 | pubmed:issn | 1875-8312 | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:BuchsbaumMont... | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:MachacJosefJ | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:FusterValenti... | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:BadimonJuan... | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:WorthleySteph... | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:HelftGérardG | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:FayadZahi AZA | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:ZamanAzfar... | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:WorthleyMatth... | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:TangCheukC | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:ZhangZhuang... | lld:pubmed |
| pubmed-article:18979182 | pubmed:author | pubmed-author:LiewGary Y... | lld:pubmed |
| pubmed-article:18979182 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18979182 | pubmed:volume | 25 | lld:pubmed |
| pubmed-article:18979182 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18979182 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18979182 | pubmed:pagination | 251-7 | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:meshHeading | pubmed-meshheading:18979182... | lld:pubmed |
| pubmed-article:18979182 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:18979182 | pubmed:articleTitle | In vivo non-invasive serial monitoring of FDG-PET progression and regression in a rabbit model of atherosclerosis. | lld:pubmed |
| pubmed-article:18979182 | pubmed:affiliation | Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Medical Center, New York, NY 10029, USA. stephen.worthley@adelaide.edu.au | lld:pubmed |
| pubmed-article:18979182 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18979182 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18979182 | lld:pubmed |
