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pubmed-article:18955670pubmed:abstractTextOral anticoagulation (OAC) therapy is effective in atrial fibrillation but requires vigilance to maintain the international normalized ratio in the therapeutic range. This report examines how differences in time in therapeutic range (TTR) between centers and between countries affect the outcomes of OAC therapy.lld:pubmed
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pubmed-article:18955670pubmed:articleTitleBenefit of oral anticoagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and countries as measured by time in therapeutic range.lld:pubmed
pubmed-article:18955670pubmed:affiliationPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada. connostu@phri.calld:pubmed
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