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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-10-23
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pubmed:abstractText |
The substitution of valine by methionine in the brain-derived neurotrophic factor (BDNF Val/Met) gene alters the intracellular trafficking and regulated secretion of BDNF. This study tested whether the BDNF Val/Met polymorphism is associated with bipolar disorder in Korean subjects, and whether clinical features vary according to genotype.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0224
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2008 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-103
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pubmed:meshHeading |
pubmed-meshheading:18843195-Adult,
pubmed-meshheading:18843195-Analysis of Variance,
pubmed-meshheading:18843195-Bipolar Disorder,
pubmed-meshheading:18843195-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:18843195-Chi-Square Distribution,
pubmed-meshheading:18843195-Female,
pubmed-meshheading:18843195-Gene Frequency,
pubmed-meshheading:18843195-Genetic Predisposition to Disease,
pubmed-meshheading:18843195-Genotype,
pubmed-meshheading:18843195-Granuloma, Lethal Midline,
pubmed-meshheading:18843195-Humans,
pubmed-meshheading:18843195-Male,
pubmed-meshheading:18843195-Methionine,
pubmed-meshheading:18843195-Middle Aged,
pubmed-meshheading:18843195-Suicide,
pubmed-meshheading:18843195-Valine
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pubmed:year |
2008
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pubmed:articleTitle |
Brain-derived neurotrophic factor Val/Met polymorphism and bipolar disorder. Association of the Met allele with suicidal behavior of bipolar patients.
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pubmed:affiliation |
Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
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pubmed:publicationType |
Journal Article
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