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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-22
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pubmed:abstractText |
Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic Stress Disorder (PTSD). A single nucleotide polymorphism (SNP) (957C>T) and a deletion polymorphism (-141delC) in the DRD2 gene and a SNP (Taq1A) in a gene directly downstream of DRD2 have all been implicated in dopamine functioning in the brain.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1520-6394
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2008 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
28-33
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18833581-Adult,
pubmed-meshheading:18833581-Alleles,
pubmed-meshheading:18833581-Australia,
pubmed-meshheading:18833581-Combat Disorders,
pubmed-meshheading:18833581-Gene Frequency,
pubmed-meshheading:18833581-Genetic Predisposition to Disease,
pubmed-meshheading:18833581-Genetic Testing,
pubmed-meshheading:18833581-Genotype,
pubmed-meshheading:18833581-Humans,
pubmed-meshheading:18833581-Male,
pubmed-meshheading:18833581-Phenotype,
pubmed-meshheading:18833581-Polymorphism, Single Nucleotide,
pubmed-meshheading:18833581-Receptors, Dopamine D2,
pubmed-meshheading:18833581-Veterans,
pubmed-meshheading:18833581-Vietnam Conflict
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pubmed:year |
2009
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pubmed:articleTitle |
The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans.
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pubmed:affiliation |
Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia. j.voisey@qut.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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