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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-11-13
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pubmed:abstractText |
Growth differentiation factor-5 (GDF-5), a member of the transforming growth factor (TGF)-beta family, is involved in joint development during embryogenesis and has the potential to regenerate cartilage in adult animals. As progression of chronic joint diseases is influenced by cytokines of the synovial tissue, we examined the expression and effects of GDF-5 in this tissue.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1502-7732
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pubmed:author |
pubmed-author:BramlageC PCP,
pubmed-author:BramlagePP,
pubmed-author:BurmesterG-RGR,
pubmed-author:HäuplTT,
pubmed-author:KappLL,
pubmed-author:KoziolekMM,
pubmed-author:KrennVV,
pubmed-author:MüllerG AGA,
pubmed-author:PrussAA,
pubmed-author:StrutzFF,
pubmed-author:UngethümUU,
pubmed-author:WesselsJJ
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pubmed:issnType |
Electronic
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
401-9
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pubmed:meshHeading |
pubmed-meshheading:18830904-Adult,
pubmed-meshheading:18830904-Aged,
pubmed-meshheading:18830904-Aged, 80 and over,
pubmed-meshheading:18830904-Antirheumatic Agents,
pubmed-meshheading:18830904-Arthritis, Rheumatoid,
pubmed-meshheading:18830904-Case-Control Studies,
pubmed-meshheading:18830904-Cell Migration Assays, Macrophage,
pubmed-meshheading:18830904-Cytokines,
pubmed-meshheading:18830904-Down-Regulation,
pubmed-meshheading:18830904-Fibroblasts,
pubmed-meshheading:18830904-Gene Expression,
pubmed-meshheading:18830904-Glucocorticoids,
pubmed-meshheading:18830904-Growth Differentiation Factor 5,
pubmed-meshheading:18830904-Humans,
pubmed-meshheading:18830904-Immunohistochemistry,
pubmed-meshheading:18830904-Immunosuppression,
pubmed-meshheading:18830904-In Situ Hybridization,
pubmed-meshheading:18830904-Methotrexate,
pubmed-meshheading:18830904-Middle Aged,
pubmed-meshheading:18830904-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18830904-Prednisolone,
pubmed-meshheading:18830904-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18830904-Synovial Membrane,
pubmed-meshheading:18830904-Tumor Necrosis Factor-alpha
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pubmed:articleTitle |
Modulatory effects of inflammation and therapy on GDF-5 expression in rheumatoid arthritis synovium.
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pubmed:affiliation |
Department of Medicine, Nephrology and Rheumatology, Georg-August-University Gottingen, Gottingen. c.bramlage@med.uni-goettingen.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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