Source:http://linkedlifedata.com/resource/pubmed/id/18826373
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
2008-10-29
|
pubmed:abstractText |
A previously healthy boy who had received varicella vaccine developed herpes zoster with meningitis. The vaccine strain recovered from scabs of 3 skin lesions had the wild-type allele at position 108111, a vaccine marker never previously associated with vaccine-associated adverse events. The vaccine strain from cerebrospinal fluid also contained mutations never previously observed at vaccine-associated single nucleotide polymorphisms that would alter amino acid sequences in ORF54 and ORF59. The presence of distinct strains in skin lesions and cerebrospinal fluid indicate that >1 variant strain may reactivate to cause herpes zoster.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0022-1899
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
198
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1444-7
|
pubmed:meshHeading |
pubmed-meshheading:18826373-Chickenpox,
pubmed-meshheading:18826373-Chickenpox Vaccine,
pubmed-meshheading:18826373-Child,
pubmed-meshheading:18826373-DNA, Viral,
pubmed-meshheading:18826373-Genetic Variation,
pubmed-meshheading:18826373-Genotype,
pubmed-meshheading:18826373-Herpes Zoster,
pubmed-meshheading:18826373-Herpesvirus 3, Human,
pubmed-meshheading:18826373-Humans,
pubmed-meshheading:18826373-Male,
pubmed-meshheading:18826373-Meningitis,
pubmed-meshheading:18826373-Sequence Alignment,
pubmed-meshheading:18826373-Skin Diseases, Viral
|
pubmed:year |
2008
|
pubmed:articleTitle |
Herpes zoster with skin lesions and meningitis caused by 2 different genotypes of the Oka varicella-zoster virus vaccine.
|
pubmed:affiliation |
Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80045-0508, USA. myron.levin@uchsc.edu
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|