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pubmed-article:18822202pubmed:abstractTextProgrammed death-1 (PD-1) up-regulation impairs virus-specific CD8+ T-cell responses during chronic viral infection. Whether PD-1 expression influences the virus-specific CD8+ T cells in humans with acute viral infection remains largely undefined. This study aims to characterize the PD-1 expression during acute hepatitis B (AHB), and further addresses the association between the PD-1 dynamics and memory T-cell formation during acute HBV infection.lld:pubmed
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pubmed-article:18822202pubmed:articleTitle[Dynamic expression of PD-1 in HBV-specific cytotoxic T lymphocytes correlates with memory T-cell development in acute hepatitis B patients].lld:pubmed
pubmed-article:18822202pubmed:affiliationInstitute of Mincrobiology Chinese Academy of Sciences, Beijing 100101, China.lld:pubmed
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