Linked Life Data

18798040

Source:http://linkedlifedata.com/resource/pubmed/id/18798040

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2009-2-23
pubmed:abstractText
Aspergillus oryzae has been used in Japanese fermentation industries for more than a thousand years. The species produces large amounts of various hydrolytic enzymes and has been successfully applied to modern biotechnology. The size of the A. oryzae genome (37.5 Mb) is very close to that of A. flavus and A. niger, and 20-30% larger than that of either A. nidulans or A. fumigatus. A. oryzae and A. flavus have exactly the same number of aspartic proteinase genes, of which each orthologous pair shares highly conserved amino acid sequences. Synteny analysis with A. fumigatus and A. nidulans showed that the A. oryzae genome has a mosaic structure consisting of syntenic and non-syntenic blocks. In the microorganisms to be compared, the density of the genes having homologs was obviously higher on the syntenic than on the non-syntenic blocks. Expression analysis by the DNA microarray supported the significantly lower expression of genes on the non-syntenic than on the syntenic blocks.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1944-0049
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1147-51
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Genomics of industrial Aspergilli and comparison with toxigenic relatives.
pubmed:affiliation
Research Institute of Cell Engineering, National Institute of Advanced Industrial Science and Technologies, Central 6, 1-1, Higashi, Tsukuba, Ibaraki 305-8566, Japan. m.machida@aist.go.jp
pubmed:publicationType
Journal Article, Comparative Study