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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1977-2-16
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pubmed:abstractText |
Aerosols of the Moloney murine sarcoma virus (MuSV-M) and leukemia virus (MuLV-M) complex (MuSV-M/MuLV-M) were generated from refluxing atomizers and then aged in rotating drums at 21 degrees C holding temperature with relative humidities ranging from 25 to 76%. The MuSV-M and MuLV-M aerosolized from the same tumor extract preparation survived almost equally at the four humidity levels. Both viruses remained viable in the airborne state for at least 2 hours after aerosolization. When mice were exposed to airborne MuSV-M/MuLV-M, no macroscopic lesions were observed in lungs or other tissues examined during the 2-month postexposure period. On the basis of this study, MuSV-M was determined unsuitable as a "model system" in which a simple aerosol dose response could be used for biohazard evaluation of oncogenic virus aerosols.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0027-8874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
775-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:187776-Aerosols,
pubmed-meshheading:187776-Animals,
pubmed-meshheading:187776-Disease Models, Animal,
pubmed-meshheading:187776-Humidity,
pubmed-meshheading:187776-Laboratory Infection,
pubmed-meshheading:187776-Leukemia, Experimental,
pubmed-meshheading:187776-Mice,
pubmed-meshheading:187776-Mice, Inbred BALB C,
pubmed-meshheading:187776-Moloney murine leukemia virus,
pubmed-meshheading:187776-Sarcoma, Experimental,
pubmed-meshheading:187776-Sarcoma Viruses, Murine,
pubmed-meshheading:187776-Time Factors
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pubmed:year |
1976
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pubmed:articleTitle |
Evaluation of Moloney murine sarcoma and leukemia virus complex as a model for airborne oncogenic virus biohazards: survival of airborne virus and exposure of mice.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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