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pubmed:abstractText |
The administration of neurotrophins has been clearly demonstrated to support survival of retina cells during a variety of insults. Increased levels of neurotrophins, such as the nerve growth factor (NGF), have been found in experimental models of glaucoma. Nevertheless, loss of retinal cells does occur in the course of ocular hypertension. Therefore, this study sought to address whether timely changes in NGF and its receptors, trkA(NGFR) and p75(NTR), might explain the progression of retinal damage during experimental glaucoma.
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pubmed:affiliation |
CIR, Laboratory of Ophthalmology, University Campus Bio-Medico, Via Alvaro del Portillo, 21, 00128, Rome, Italy.
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