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pubmed-article:18727922pubmed:abstractTextThe cytochrome P450 isoenzyme 3A5 (CYP3A5) has an important role on biotransformation of xenobiotics. CYP3A5 SNPs have been associated with variations on enzyme activity that can modify the metabolism of several drugs.lld:pubmed
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pubmed-article:18727922pubmed:articleTitleCYP3A53A allele is associated with reduced lowering-lipid response to atorvastatin in individuals with hypercholesterolemia.lld:pubmed
pubmed-article:18727922pubmed:affiliationDepartment Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil. malicewi@usp.brlld:pubmed
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