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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2008-11-3
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pubmed:abstractText |
Congenital heart disease (CHD) is the most common birth defect and affects nearly 1% of newborns. The aetiology of CHD is largely unknown and only a small percentage can be assigned to environmental risk factors such as maternal diseases or exposure to mutagenic agents during pregnancy. Chromosomal imbalances have been identified in many forms of syndromic CHD, but very little is known about the impact of DNA copy number changes in non-syndromic CHD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1468-6244
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pubmed:author |
pubmed-author:ChenWW,
pubmed-author:ErdoganFF,
pubmed-author:JacobsenJ RJR,
pubmed-author:JurkatisJJ,
pubmed-author:LarsenL ALA,
pubmed-author:RopersH-HHH,
pubmed-author:SchubertMM,
pubmed-author:TümerZZ,
pubmed-author:TommerupNN,
pubmed-author:TzschachAA,
pubmed-author:UllmannRR,
pubmed-author:ZhangLL
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pubmed:issnType |
Electronic
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
704-9
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pubmed:meshHeading |
pubmed-meshheading:18713793-Child,
pubmed-meshheading:18713793-Chromosome Aberrations,
pubmed-meshheading:18713793-Chromosome Deletion,
pubmed-meshheading:18713793-Comparative Genomic Hybridization,
pubmed-meshheading:18713793-Cytogenetic Analysis,
pubmed-meshheading:18713793-Female,
pubmed-meshheading:18713793-Gene Dosage,
pubmed-meshheading:18713793-Gene Duplication,
pubmed-meshheading:18713793-Genome, Human,
pubmed-meshheading:18713793-Heart Defects, Congenital,
pubmed-meshheading:18713793-Humans,
pubmed-meshheading:18713793-Infant,
pubmed-meshheading:18713793-Infant, Newborn,
pubmed-meshheading:18713793-Male,
pubmed-meshheading:18713793-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18713793-Phenotype
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pubmed:year |
2008
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pubmed:articleTitle |
High frequency of submicroscopic genomic aberrations detected by tiling path array comparative genome hybridisation in patients with isolated congenital heart disease.
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pubmed:affiliation |
Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195 Berlin, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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