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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1991-9-11
|
| pubmed:abstractText |
The geometry of liver functional micro-units is described in the light of the immunohistologic features of human hepatocytes stained with a retinol-binding protein antibody. The stained cells were distributed into two ordered sets which provided a provisional representation of the law regulating both the motion and the alternation of the rest-work phases (homopoiesis and homorhesis configurations, respectively) which reflect bistable liver micro-unit equilibrium (auto-isodiasostasis). Oscillations between the HP and HR states generate a relaxation cycle that can be assumed to be shared by all micro-units and to be regulated by feedback mechanisms. A model illustrating the compactness of the liver's global action as a result of the activity of each micro-unit is also proposed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0390-5748
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
21
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
41-68
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading | |
| pubmed:articleTitle |
Liver system. IV. More on the liver micro-unit: physics and geometry of its action.
|
| pubmed:affiliation |
Istituto di Medicina Interna, Università degli Studi di Milano.
|
| pubmed:publicationType |
Journal Article,
Review
|