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pubmed-article:18594010pubmed:abstractTextThe EML4-ALK fusion gene has been detected in approximately 7% of Japanese non-small cell lung cancers (NSCLC). We determined the frequency of EML4-ALK in Caucasian NSCLC and in NSCLC cell lines. We also determined whether TAE684, a specific ALK kinase inhibitor, would inhibit the growth of EML4-ALK-containing cell lines in vitro and in vivo.lld:pubmed
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pubmed-article:18594010pubmed:articleTitleEML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer.lld:pubmed
pubmed-article:18594010pubmed:affiliationLowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, D820A, 44 Binney Street, Boston, MA 02115, USA.lld:pubmed
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