Linked Life Data

18580292

Source:http://linkedlifedata.com/resource/pubmed/id/18580292

Statements in which the resource exists.
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pubmed-article:18580292pubmed:abstractTextHuman exposure to cold stimulates cutaneous vasoconstriction by activating both sympathetic reflex and locally mediated pathways. Older humans are vulnerable to hypothermia because primary aging impairs thermoregulatory cutaneous vasoconstriction. This article highlights recent findings discussing how age-related decrements in sympathetic neurotransmission contribute directly to thermoregulatory impairment, whereas changes in local cold-induced intracellular signaling suggest a more generalized age-associated vascular dysfunction.lld:pubmed
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pubmed-article:18580292pubmed:articleTitleAltered mechanisms of thermoregulatory vasoconstriction in aged human skin.lld:pubmed
pubmed-article:18580292pubmed:affiliationDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. cthomp44@jhmi.edulld:pubmed
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