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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-5-26
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pubmed:abstractText |
Mutations of the base excision repair gene MUTYH have been reported as underlying genetic defects in autosomal-recessive familial adenomatous polyposis (FAP). Our aim was to determine the frequency of the most common mutations (p.Tyr165Cys and p.Gly382Asp) in patients with strong evidence for familial colorectal cancer (fCRC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1574-0153
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pubmed:author |
pubmed-author:AretzStefanS,
pubmed-author:BeckerUrsulaU,
pubmed-author:BuettnerReinhardR,
pubmed-author:FriedrichsNicolausN,
pubmed-author:GrünhageFrankF,
pubmed-author:JungckMatthiasM,
pubmed-author:LambertiChristofC,
pubmed-author:LammertFrankF,
pubmed-author:PlassmannDominikD,
pubmed-author:RahnerNilsN,
pubmed-author:SauerbruchTilmanT,
pubmed-author:Schulte-WitteHildegardH
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
55-61
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pubmed:meshHeading |
pubmed-meshheading:18503156-Aged,
pubmed-meshheading:18503156-Colorectal Neoplasms,
pubmed-meshheading:18503156-DNA Glycosylases,
pubmed-meshheading:18503156-Female,
pubmed-meshheading:18503156-Genetic Predisposition to Disease,
pubmed-meshheading:18503156-Germany,
pubmed-meshheading:18503156-Humans,
pubmed-meshheading:18503156-Male,
pubmed-meshheading:18503156-Middle Aged,
pubmed-meshheading:18503156-Mutation,
pubmed-meshheading:18503156-Polymerase Chain Reaction
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pubmed:year |
2008
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pubmed:articleTitle |
Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer.
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pubmed:affiliation |
Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Bonn, Germany. frank.gruenhage@ukb.uni-bonn.de
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pubmed:publicationType |
Journal Article
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