rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2008-5-23
|
pubmed:abstractText |
Severe sepsis activates the hypothalamopituitary axis, increasing cortisol production. In some studies, hydrocortisone substitution based on an adrenocorticotropic hormone-stimulation test or baseline cortisol measurement has improved outcome. Because only the free fraction of cortisol is active, measurement of free cortisol may be more important than total cortisol in critically ill patients. We measured total and free cortisol in patients with severe sepsis and related the concentrations to outcome.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1526-7598
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
106
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1813-9
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:18499615-Adrenal Cortex Function Tests,
pubmed-meshheading:18499615-Adrenal Insufficiency,
pubmed-meshheading:18499615-Adult,
pubmed-meshheading:18499615-Biological Markers,
pubmed-meshheading:18499615-Female,
pubmed-meshheading:18499615-Finland,
pubmed-meshheading:18499615-Hospital Mortality,
pubmed-meshheading:18499615-Humans,
pubmed-meshheading:18499615-Hydrocortisone,
pubmed-meshheading:18499615-Kaplan-Meier Estimate,
pubmed-meshheading:18499615-Male,
pubmed-meshheading:18499615-Predictive Value of Tests,
pubmed-meshheading:18499615-Prospective Studies,
pubmed-meshheading:18499615-Sepsis,
pubmed-meshheading:18499615-Severity of Illness Index,
pubmed-meshheading:18499615-Shock, Septic,
pubmed-meshheading:18499615-Treatment Outcome
|
pubmed:year |
2008
|
pubmed:articleTitle |
Free cortisol in sepsis and septic shock.
|
pubmed:affiliation |
Department of Intensive Care, Kuopio University Hospital, PL 16222 Kuopio, Finland. Stepani.Bendel@kuh.fi
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|