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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
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|
pubmed:dateCreated |
2008-5-16
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|
pubmed:abstractText |
The activity of imatinib in leukemia has recently been linked with expression of the organic cation transporter 1 (OCT1) gene SLC22A1. Here, we characterized the contribution of solute carriers to imatinib transport in an effort to further understand mechanisms involved in the intracellular uptake and retention (IUR) of the drug.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3141-8
|
|
pubmed:meshHeading |
pubmed-meshheading:18483382-Animals,
pubmed-meshheading:18483382-Antineoplastic Agents,
pubmed-meshheading:18483382-Cell Line, Tumor,
pubmed-meshheading:18483382-Drug Resistance, Neoplasm,
pubmed-meshheading:18483382-Gastrointestinal Stromal Tumors,
pubmed-meshheading:18483382-Gene Expression,
pubmed-meshheading:18483382-Humans,
pubmed-meshheading:18483382-Organic Cation Transporter 1,
pubmed-meshheading:18483382-Piperazines,
pubmed-meshheading:18483382-Polymerase Chain Reaction,
pubmed-meshheading:18483382-Pyrimidines,
pubmed-meshheading:18483382-Xenopus laevis
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
Interaction of imatinib with human organic ion carriers.
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|
pubmed:affiliation |
Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphia, TN 38105, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
