Source:http://linkedlifedata.com/resource/pubmed/id/18482815
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
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| pubmed:dateCreated |
2008-7-21
|
| pubmed:databankReference | |
| pubmed:abstractText |
Prevalence and characteristics of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in Korean hospitals were assessed. A total of 1484 clinical Enterobacteriaceae isolates were collected from 8 tertiary-care hospitals in various regions of Korea over a 3-month period (June to August) in 2005. Among 546 Klebsiella pneumoniae isolates, 123 isolates (22.4%) showed ESBL-producing activity, and 47 (10.2%) of 460 isolates of Escherichia coli were ESBL producers. Of the Enterobacter cloacae isolates, 16.2% (17/105) evidenced ESBL-producing activity. The most prevalent ESBLs were SHV-12 and CTX-M-14 in K. pneumoniae and E. coli, respectively. In E. cloacae, SHV-12 was also the most prevalent. Prevalence of ESBL production differed among the specimens. Although the K. pneumoniae isolates from urine and aspirates evidenced high ESBL production rates (35.4% and 57.1%, respectively), those from sputum, blood, and pus showed relatively low ESBL production rates (17.0%, 14.8%, and 5.3%, respectively). However, E. coli isolates obtained from sputum showed significantly higher ESBL production rates (37.5%) than were seen in samples obtained from other sources, but those obtained from urine showed lower ESBL production rates (8.3%). These significant differences in ESBL-producing K. pneumoniae and E. coli isolates among the isolated specimens should be examined further, with an eye toward the implications of this research in clinical settings.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
0732-8893
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| pubmed:author |
pubmed-author:ChangHyun-HaHH,
pubmed-author:ChungDoo-RyeonDR,
pubmed-author:JungDong SikDS,
pubmed-author:JungSook-InSI,
pubmed-author:KiHyun KyunHK,
pubmed-author:KimShin-WooSW,
pubmed-author:KimYeon-SookYS,
pubmed-author:KoKwan SooKS,
pubmed-author:KwonKi TaeKT,
pubmed-author:LeeHyuckH,
pubmed-author:LeeMi YoungMY,
pubmed-author:LeeNam YongNY,
pubmed-author:PeckKyong RanKR,
pubmed-author:SongJae-HoonJH,
pubmed-author:YeomJoon-SupJS
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| pubmed:issnType |
Print
|
| pubmed:volume |
61
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
453-9
|
| pubmed:meshHeading |
pubmed-meshheading:18482815-Anti-Bacterial Agents,
pubmed-meshheading:18482815-Blood,
pubmed-meshheading:18482815-DNA, Bacterial,
pubmed-meshheading:18482815-Enterobacter cloacae,
pubmed-meshheading:18482815-Enterobacteriaceae Infections,
pubmed-meshheading:18482815-Escherichia coli,
pubmed-meshheading:18482815-Hospitals,
pubmed-meshheading:18482815-Humans,
pubmed-meshheading:18482815-Klebsiella pneumoniae,
pubmed-meshheading:18482815-Korea,
pubmed-meshheading:18482815-Microbial Sensitivity Tests,
pubmed-meshheading:18482815-Molecular Sequence Data,
pubmed-meshheading:18482815-Sequence Analysis, DNA,
pubmed-meshheading:18482815-Sputum,
pubmed-meshheading:18482815-Suppuration,
pubmed-meshheading:18482815-Urine,
pubmed-meshheading:18482815-beta-Lactam Resistance,
pubmed-meshheading:18482815-beta-Lactamases,
pubmed-meshheading:18482815-beta-Lactams
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Prevalence and characterization of extended-spectrum beta-lactamase-producing Enterobacteriaceae isolated in Korean hospitals.
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| pubmed:affiliation |
Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, Korea.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|