rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-6-9
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pubmed:abstractText |
NTDs are considered complex disorders that arise from an interaction between genetic and environmental factors. NTD family 8776 is a large multigenerational Caucasian family that provides a unique resource for the genetic analysis of NTDs. Previous linkage analysis using a genome-wide SNP screen in family 8776 with multipoint nonparametric mapping methods identified maximum LOD* scores of approximately 3.0 mapping to 2q33.1-q35 and 7p21.1-pter.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
pubmed:issn |
1542-0760
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pubmed:author |
pubmed-author:Ashley-KochAllisonA,
pubmed-author:ConnellyJessica JJJ,
pubmed-author:EllisNathenN,
pubmed-author:GeorgeTimothy MTM,
pubmed-author:GilbertJohn RJR,
pubmed-author:GregorySimon GSG,
pubmed-author:MehltretterLorraineL,
pubmed-author:NTD Collaborative Group,
pubmed-author:SiegelDeborah GDG,
pubmed-author:SpeerMarcy CMC,
pubmed-author:StammDemetra SDS,
pubmed-author:StephanDietrich ADA,
pubmed-author:TrottAlisonA,
pubmed-author:VekemansMichelM,
pubmed-author:ZismannVictoriaV
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pubmed:copyrightInfo |
Copyright 2008 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
441-52
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18452155-Chromosomes, Human, Pair 2,
pubmed-meshheading:18452155-Chromosomes, Human, Pair 7,
pubmed-meshheading:18452155-Female,
pubmed-meshheading:18452155-Genetic Linkage,
pubmed-meshheading:18452155-Genetic Predisposition to Disease,
pubmed-meshheading:18452155-Genotype,
pubmed-meshheading:18452155-Humans,
pubmed-meshheading:18452155-Male,
pubmed-meshheading:18452155-Neural Tube Defects,
pubmed-meshheading:18452155-Pedigree
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pubmed:year |
2008
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pubmed:articleTitle |
Refinement of 2q and 7p loci in a large multiplex NTD family.
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pubmed:affiliation |
Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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