rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-4-8
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pubmed:abstractText |
Changes in the properties of visceral sensory neurons contribute to the development of gastrointestinal pain. However, little is known about the molecules involved in mechanosensation from the gastrointestinal tract. We investigated the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2), a member of the mitogen-activated protein kinase cascade, in dorsal root ganglion (DRG) and nodose ganglion (NG) neurons by noxious gastric distention (GD) and its involvement in acute visceral pain in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ASIC channel,
http://linkedlifedata.com/resource/pubmed/chemical/Butadienes,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Neurofilament Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitriles,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/TRPV Cation Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Trpv1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/U 0126,
http://linkedlifedata.com/resource/pubmed/chemical/neurofilament protein H
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1528-0012
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pubmed:author |
pubmed-author:DaiYiY,
pubmed-author:KobayashiKimikoK,
pubmed-author:KondoTakashiT,
pubmed-author:MatsumotoTakayukiT,
pubmed-author:MiwaHirotoH,
pubmed-author:MiyoshiKanK,
pubmed-author:NoguchiKoichiK,
pubmed-author:ObataKoichiK,
pubmed-author:OzakiNoriyukiN,
pubmed-author:SakuraiJunJ,
pubmed-author:SugiuraYasuoY,
pubmed-author:TokunagaAtsushiA,
pubmed-author:YamanakaHirokiH
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pubmed:issnType |
Electronic
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pubmed:volume |
134
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1094-103
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18395090-Abdominal Pain,
pubmed-meshheading:18395090-Acute Disease,
pubmed-meshheading:18395090-Animals,
pubmed-meshheading:18395090-Balloon Dilation,
pubmed-meshheading:18395090-Butadienes,
pubmed-meshheading:18395090-Disease Models, Animal,
pubmed-meshheading:18395090-Electromyography,
pubmed-meshheading:18395090-Enzyme Activation,
pubmed-meshheading:18395090-Enzyme Inhibitors,
pubmed-meshheading:18395090-Ganglia, Spinal,
pubmed-meshheading:18395090-Gastric Emptying,
pubmed-meshheading:18395090-Immunohistochemistry,
pubmed-meshheading:18395090-Male,
pubmed-meshheading:18395090-Membrane Proteins,
pubmed-meshheading:18395090-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:18395090-Nerve Tissue Proteins,
pubmed-meshheading:18395090-Neurofilament Proteins,
pubmed-meshheading:18395090-Neurons, Afferent,
pubmed-meshheading:18395090-Nitriles,
pubmed-meshheading:18395090-Nodose Ganglion,
pubmed-meshheading:18395090-Physical Stimulation,
pubmed-meshheading:18395090-Rats,
pubmed-meshheading:18395090-Rats, Sprague-Dawley,
pubmed-meshheading:18395090-Sodium Channels,
pubmed-meshheading:18395090-Stomach,
pubmed-meshheading:18395090-TRPV Cation Channels
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pubmed:year |
2008
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pubmed:articleTitle |
Activation of extracellular signal-regulated protein kinase in sensory neurons after noxious gastric distention and its involvement in acute visceral pain in rats.
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pubmed:affiliation |
Department of Anatomy and Neuroscience, Hyogo College of Medicine, Mukogawa-cho, Nishinomiya, Hyogo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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