Linked Life Data

18323037

Source:http://linkedlifedata.com/resource/pubmed/id/18323037

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-3-7
pubmed:abstractText
The biochemical markers of bone remodeling reflect the rates of bone resorption and bone formation in the whole body rather than in segments of the skeleton. The markers cannot be used for a diagnosis of bone disease. However, they are a valuable tool in the differential diagnosis, in the assessment of fracture risk independent of bone mineral density and, in the monitoring treatments of metabolic and neoplastic bone diseases as well as the side effects of some drugs on bone (e.g., adjuvant treatment with selective inhibitors of aromatase). This review provides characteristics of the markers currently used to assess neoplastic bone diseases and, their clinical values for stratification and monitoring treatments. Currently used markers provide sufficient specificity. However, their sensitivities under various clinical situations have to be respected. The clinical utility of the markers requires their standardization and availability.
pubmed:language
cze
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0008-7335
pubmed:author
pubmed:issnType
Print
pubmed:volume
147
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-13
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[Clinical utility of bone markers in the evaluation and follow-up in patients with neoplastic bone diseases].
pubmed:affiliation
Revmatologický ústav, Praha. stepan@revma.cz
pubmed:publicationType
Journal Article, English Abstract, Review