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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-3-4
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pubmed:abstractText |
The C677T polymorphism of methylene tetrahydrofolate reductase (MTHFR) lowers the activity of this enzyme, producing moderate elevation of blood levels of homocysteine (Hcy) and lowering the levels of 5-methyl-tetrahydro-folic acid (5-MeTHFA), methionine (Meth), and S-adenosylmethionine (SAM). In this study we examined 100 apparently normal subjects of both sexes (average age 25.6 +/- 4.25) for the genotypic presence of the T allele and its association with accommodative amplitude (AA).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1040-5488
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
196-200
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18317335-Accommodation, Ocular,
pubmed-meshheading:18317335-Adult,
pubmed-meshheading:18317335-Female,
pubmed-meshheading:18317335-Folic Acid,
pubmed-meshheading:18317335-Genetic Variation,
pubmed-meshheading:18317335-Genotype,
pubmed-meshheading:18317335-Homocysteine,
pubmed-meshheading:18317335-Humans,
pubmed-meshheading:18317335-Male,
pubmed-meshheading:18317335-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:18317335-Polymerase Chain Reaction,
pubmed-meshheading:18317335-Polymorphism, Single Nucleotide,
pubmed-meshheading:18317335-Vision, Binocular
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pubmed:year |
2008
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pubmed:articleTitle |
C677T methylene-H4-folate-reductase variant decreases binocular accommodation.
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pubmed:affiliation |
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA. clkb@uab.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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