Linked Life Data

18316020

Source:http://linkedlifedata.com/resource/pubmed/id/18316020

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-3-4
pubmed:abstractText
Cannabinoid signaling by CB1 receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB1 receptors.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/2-arachidonylglycerol, http://linkedlifedata.com/resource/pubmed/chemical/Arachidonic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Carnitine O-Palmitoyltransferase, http://linkedlifedata.com/resource/pubmed/chemical/Endocannabinoids, http://linkedlifedata.com/resource/pubmed/chemical/Ethanol, http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acid Synthetase Complex, http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, http://linkedlifedata.com/resource/pubmed/chemical/Glycerides, http://linkedlifedata.com/resource/pubmed/chemical/Lipoprotein Lipase, http://linkedlifedata.com/resource/pubmed/chemical/Piperidines, http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Cannabinoid, CB1, http://linkedlifedata.com/resource/pubmed/chemical/Srebf1 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Sterol Regulatory Element Binding..., http://linkedlifedata.com/resource/pubmed/chemical/rimonabant
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1550-4131
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-8
pubmed:meshHeading
pubmed-meshheading:18316020-Animals, pubmed-meshheading:18316020-Arachidonic Acids, pubmed-meshheading:18316020-Carnitine O-Palmitoyltransferase, pubmed-meshheading:18316020-Cells, Cultured, pubmed-meshheading:18316020-Diet, Fat-Restricted, pubmed-meshheading:18316020-Disease Models, Animal, pubmed-meshheading:18316020-Endocannabinoids, pubmed-meshheading:18316020-Ethanol, pubmed-meshheading:18316020-Fatty Acid Synthetase Complex, pubmed-meshheading:18316020-Fatty Acids, pubmed-meshheading:18316020-Fatty Liver, Alcoholic, pubmed-meshheading:18316020-Glycerides, pubmed-meshheading:18316020-Hepatocytes, pubmed-meshheading:18316020-Humans, pubmed-meshheading:18316020-Lipogenesis, pubmed-meshheading:18316020-Lipoprotein Lipase, pubmed-meshheading:18316020-Liver, pubmed-meshheading:18316020-Mice, pubmed-meshheading:18316020-Oxidation-Reduction, pubmed-meshheading:18316020-Paracrine Communication, pubmed-meshheading:18316020-Piperidines, pubmed-meshheading:18316020-Pyrazoles, pubmed-meshheading:18316020-Receptor, Cannabinoid, CB1, pubmed-meshheading:18316020-Sterol Regulatory Element Binding Protein 1, pubmed-meshheading:18316020-Up-Regulation
pubmed:year
2008
pubmed:articleTitle
Cannabinoids provoke alcoholic steatosis through a conspiracy of neighbors.
pubmed:affiliation
Division of Liver Diseases, Mount Sinai School of Medicine, New York, NY 10029, USA. scott.friedman@mssm.edu
pubmed:publicationType
Journal Article, Comment