Source:http://linkedlifedata.com/resource/pubmed/id/18251784
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-2-6
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pubmed:abstractText |
Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the prostate is rare, and only five cases have been reported. Reported herein is a new case that has involved a 9 year follow up. A 79-year-old man was treated with transurethral resection (TUR) for a mass of the right prostatic lobe, and followed up under a diagnosis of benign prostatic hyperplasia with atypical lymphoid infiltration. Seven years later TUR was again performed for a right lobe mass. The lesion was diagnosed as a relapsed MALT lymphoma after detailed histological and immunoglobulin heavy chain gene analyses of the initial and relapsed lesions. Interestingly, lymphoepithelial lesions were observed only infrequently in this tumor. The API2-MALT1 fusion, a gene alteration specific to MALT lymphoma, was absent. The patient had stage IA disease at the time of tumor relapse, and has been alive and well for the 2 years after the second TUR. The present case suggests that despite tumor recurrence, prostatic MALT lymphoma is indolent, and function-preserving therapy is warranted.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1440-1827
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
191-5
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pubmed:meshHeading |
pubmed-meshheading:18251784-Aged,
pubmed-meshheading:18251784-Clone Cells,
pubmed-meshheading:18251784-DNA, Neoplasm,
pubmed-meshheading:18251784-Humans,
pubmed-meshheading:18251784-Immunoglobulin Heavy Chains,
pubmed-meshheading:18251784-Lymphoma, B-Cell, Marginal Zone,
pubmed-meshheading:18251784-Magnetic Resonance Imaging,
pubmed-meshheading:18251784-Male,
pubmed-meshheading:18251784-Neoplasm Recurrence, Local,
pubmed-meshheading:18251784-Neoplasm Staging,
pubmed-meshheading:18251784-Prostate,
pubmed-meshheading:18251784-Prostatic Neoplasms,
pubmed-meshheading:18251784-Transurethral Resection of Prostate,
pubmed-meshheading:18251784-Treatment Outcome,
pubmed-meshheading:18251784-Tumor Markers, Biological
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pubmed:year |
2008
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pubmed:articleTitle |
Primary mucosa-associated lymphoid tissue lymphoma of the prostate: tumor relapse 7 years after local therapy.
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pubmed:affiliation |
Department of Pathology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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