| pubmed-article:18243698 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18243698 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:18243698 | lifeskim:mentions | umls-concept:C0268563 | lld:lifeskim |
| pubmed-article:18243698 | lifeskim:mentions | umls-concept:C1420466 | lld:lifeskim |
| pubmed-article:18243698 | lifeskim:mentions | umls-concept:C0600115 | lld:lifeskim |
| pubmed-article:18243698 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:18243698 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:18243698 | pubmed:dateCreated | 2008-3-10 | lld:pubmed |
| pubmed-article:18243698 | pubmed:abstractText | Tricyclic 6,7-dihydro-4H-pyrazolo[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione was identified as a novel scaffold for Aurora kinase A inhibition through virtual screening. SAR exploration coupled with molecular modeling of 8a reveals the minimum pharmacophore requirements for Aurora kinase A inhibition. | lld:pubmed |
| pubmed-article:18243698 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18243698 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18243698 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18243698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18243698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18243698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18243698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18243698 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18243698 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18243698 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:18243698 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:HsiehHsing-Pa... | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:ChaoYu-ShengY... | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:TanUan-KangUK | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:ChangChung-Yu... | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:WuSu-YingSY | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:HsuJohn T-AJT | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:CoumarMohane... | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:LinWen-HsingW... | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:ChangTeng-Yua... | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:WuJian-SungJS | lld:pubmed |
| pubmed-article:18243698 | pubmed:author | pubmed-author:LeouJiun-Shya... | lld:pubmed |
| pubmed-article:18243698 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18243698 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:18243698 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:18243698 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18243698 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18243698 | pubmed:pagination | 1623-7 | lld:pubmed |
| pubmed-article:18243698 | pubmed:dateRevised | 2011-7-11 | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:meshHeading | pubmed-meshheading:18243698... | lld:pubmed |
| pubmed-article:18243698 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18243698 | pubmed:articleTitle | Aurora kinase A inhibitors: identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold. | lld:pubmed |
| pubmed-article:18243698 | pubmed:affiliation | Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, No. 35, Keyan Road, Zhunan Town, Miaoli County 350, Taiwan, ROC. | lld:pubmed |
| pubmed-article:18243698 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18243698 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:18243698 | lld:chembl |
