Linked Life Data

18234369

Source:http://linkedlifedata.com/resource/pubmed/id/18234369

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-3-24
pubmed:abstractText
There does not appear to be a relationship between peak oxygen consumption (VO(2)) and body mass index (BMI) in patients with heart failure (HF). We assessed the hypothesis that BMI and the oxygen uptake efficiency slope (OUES) would be related. Three hundred and thirty-seven HF patients (280 male/57 female, mean age: 56.5+/-14.1 years, resting left ventricular ejection fraction: 35.1+/-14.2%, BMI: 29.3+/-6.2 kg/m(2)) underwent cardiopulmonary exercise testing where peak VO(2) and the OUES (VO(2)=a log(10)VE+b, units: L/min) were determined. Pearson product moment correlation analysis revealed that the correlation between BMI and the OUES was significant (r=0.32, p<0.001). Furthermore, the OUES was prognostically significant in normal weight (optimal threshold: <or=/>1.2, hazard ratio: 3.7, 95% confidence interval: 1.4-9.9, p=0.01), overweight (optimal threshold: <or=/>1.5, hazard ratio: 3.9, 95% confidence interval: 1.3-11.1, p=0.01) and obese (optimal threshold: <or=/>1.7, hazard ratio: 4.1, 95% confidence interval: 1.4-12.8, p=0.01) subgroups. The OUES appears to improve with body weight in patients with HF. Furthermore, the OUES appears to be a significant prognostic marker irrespective of BMI although the optimal threshold value may differ according to body weight.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1874-1754
pubmed:author
pubmed:issnType
Electronic
pubmed:day
10
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
270-2
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The influence of body mass index on the oxygen uptake efficiency slope in patients with heart failure.
pubmed:publicationType
Letter, Comparative Study, Multicenter Study