Linked Life Data

18217981

Source:http://linkedlifedata.com/resource/pubmed/id/18217981

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2008-10-1
pubmed:abstractText
A considerable number of biochemical and physiologic studies evaluate the roles of gonadotropins in carcinogenesis. Latest reports show that human chorionic gonadotropin (hCG), and especially its beta subunit, are secreted by a variety of malignant tumors of different origin. However, the mechanism of hCG action and its role in tumor development is not known yet. This study, with the help of reverse transcription-polymerase chain reaction and immunohistochemistry, is an attempt to document the molecular presence of the hCGbeta and luteinizing hormone/hCG receptor (LH/hCGR) in the ovarian, endometrial, and uterine cervix cancer tissues. The LH/hCGR, coexpressed with hCGbeta, may act as a potential mediator of hCG action in nontrophoblastic gynecological cancers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1525-1438
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1102-7
pubmed:meshHeading
pubmed:articleTitle
Coexpression of human chorionic gonadotropin beta subunit and its receptor in nontrophoblastic gynecological cancer.
pubmed:affiliation
Department of Cell Biology, University of Medical Sciences, Poznan, Poland. ajanko@amp.edu.pl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't