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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-2-12
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pubmed:abstractText |
Traditional antiarrhythmic pharmacological therapies are limited by their global cardiac action, low efficacy, and significant proarrhythmic effects. We present a novel approach for the modification of the myocardial electrophysiological substrate using cell grafts genetically engineered to express specific ionic channels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
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pubmed:issn |
1524-4539
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:day |
12
|
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pubmed:volume |
117
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
720-31
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pubmed:meshHeading |
pubmed-meshheading:18212286-Action Potentials,
pubmed-meshheading:18212286-Analysis of Variance,
pubmed-meshheading:18212286-Animals,
pubmed-meshheading:18212286-Animals, Newborn,
pubmed-meshheading:18212286-Arrhythmias, Cardiac,
pubmed-meshheading:18212286-Cells, Cultured,
pubmed-meshheading:18212286-Computer Simulation,
pubmed-meshheading:18212286-Electrophysiology,
pubmed-meshheading:18212286-Fibroblasts,
pubmed-meshheading:18212286-Gene Therapy,
pubmed-meshheading:18212286-Male,
pubmed-meshheading:18212286-Myocytes, Cardiac,
pubmed-meshheading:18212286-Potassium Channels, Voltage-Gated,
pubmed-meshheading:18212286-Rats,
pubmed-meshheading:18212286-Rats, Sprague-Dawley,
pubmed-meshheading:18212286-Transfection
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pubmed:year |
2008
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pubmed:articleTitle |
Cell therapy for modification of the myocardial electrophysiological substrate.
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pubmed:affiliation |
Sohnis Laboratory for Cardiac Electrophysiology and Regenerative Medicine, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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